"2017-06-09" . . "production" . "http://orcid.org/0000-0003-2533-9548" . . "ACTB_MF_812" . "Rationale: The authors use a fluorescently labeled overexpression of human b-actin to study the dynamics (G-actin/F-actin transitions) of the actin cytoskeleton in dendritic spines. As inferred by the curator and based on the author's intent it is derived that the b-actin gene provides the structural basis of the F-actin skeleton at the postsynapse.\n\nThe \"structural component\" term is derived from Fig.4 where local application of the actin polymerization inhibitor Latrunculi A resulted in reduction of actin distribution in the synapse and the retraction of the spine. For this reason this term is not annotated against a IC evidence code.. Experimental description: The annotation of ACTB is made against the human protein since a human OE protein was used; the neurons used were of rat origin." . "https://syngo.vu.nl" .