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Rationale: The paper examines the localization of kappa-type opioid receptor in dopaminergic terminals at the nucleus Accumbens using electron microscopic immunocytochemistry. Fig. 4 shows a DAT-containing terminal in contact with kappa-type immunoreactive dendritic spines. The dendritic spine shows kappa-type opioid receptor labeling at the postsynaptic density and along extrasynaptic portions of the plasma membrane. The fraction of kappa-type opioid receptor immunoreactivities which opposes DAT labeling is quantified in table 1. 2/7/2017 Pim - Based on the known transmembrane topology of the protein, the "integral component of ... membrane" term was chosen.. Experimental description: 'Rats were anesthetized with 100 mg/kg i.p. sodium pentobarbital and perfused through the ascending aorta with 1) 10 ml of heparin (1,000 U/ml) in saline; 2) 50 ml of 3.75% acrolein (Polysciences, Warrington, PA)'

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  • Rationale: The paper examines the localization of kappa-type opioid receptor in dopaminergic terminals at the nucleus Accumbens using electron microscopic immunocytochemistry. Fig. 4 shows a DAT-containing terminal in contact with kappa-type immunoreactive dendritic spines. The dendritic spine shows kappa-type opioid receptor labeling at the postsynaptic density and along extrasynaptic portions of the plasma membrane. The fraction of kappa-type opioid receptor immunoreactivities which opposes DAT labeling is quantified in table 1. 2/7/2017 Pim - Based on the known transmembrane topology of the protein, the "integral component of ... membrane" term was chosen.. Experimental description: 'Rats were anesthetized with 100 mg/kg i.p. sodium pentobarbital and perfused through the ascending aorta with 1) 10 ml of heparin (1,000 U/ml) in saline; 2) 50 ml of 3.75% acrolein (Polysciences, Warrington, PA)'
Title
  • Oprk1_CC_863
Date
  • 2017-07-02
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