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  • Rule: ActivityStreamsMapasEquivalentb3sb3sifpccisofacetshttp://demo.openlinksw.com/dataspacehttp://www.w3.org/2002/07/owl#ldpoplwebrel-me-authskos-transsql-vdb-data-lakeurn:ALKAdatareducedurn:analytics:acqof:ruleurn:clothing:rule:qaurn:det:rdf:labelurn:inference:oplfaq:ruleurn:inference:product:feature:inverse:ruleurn:ingleng:inf:demo:inf:ruleurn:kbpedia:actor:subclass:test:rulesurn:kbpedia:comedian:owl:equivalent:class:subproperty:inference:rulesurn:kbpedia:mime-artist:owl:equivalent:class:subproperty:inference:rulesurn:kbpedia:owl:equivalent:class:subproperty:inference:rulesurn:kbpedia:philosopher:owl:equivalent:class:subproperty:inference:rulesurn:kbpedia:stage-actor:owl:equivalent:class:subproperty:inference:rulesurn:kgdemo:1:ifp:ruleurn:kgdemo:1:ifp:rule2urn:lava:demo:ruleurn:owl:equivalent:class:inference:rulesurn:rdfs:subclass:subproperty:inference:rulesurn:rdfs:type:wikidata:ruleurn:recon:data:ifpurn:recon:data:ifp:ruleurn:recruitment:rule:built-in:ruleurn:rsm12e:translation:ruleurn:rxnorm:data:ruleurn:se:demo:inference:ruleurn:test:skos:inverse:ruleurn:wireless:plans:features:builtin:inference:rule:1virtrdf-eturtle-containersvirtrdf-hashtagvirtrdf-ifpvirtrdf-labelvirtrdf-meta-entity-classvirtrdf-urlNone
    
  • Inverse Functional Properties: Disabled (fastest) Apply to subjects only Apply to objects only Apply to both subjects and objects
  • "Same As": Disabled (fastest) Apply to subjects only Apply to objects only Apply to both subjects and objects (recommended) Apply to subjects, objects and predicates (not recommended on big datasets) Apply to predicates only (special use cases only)

Rationale: The noradrenaline/norepinephrine transporter (NET) mediates noradrenaline uptake. NET-KO mice exhibit reduced binding of radiolabelled desipramine (a noradrenaline re-uptake inhibitor that binds NET) to brain membranes (Fig. 1d). Further, the authors state in the text that synaptosomes from cerebral cortex and cerebellum of NET-KO mice show no radiolabelled noradrenaline uptake, which could be inhibited by noradrenaline re-uptake inhibitors (data not shown). Cyclic voltammetry from tissue slices revealed that noradrenaline clearance after electrical stimulation is affected in NET-KO mice (Fig. 2c) and quantitative in vivo microdialysis showed that KO animals exhibit higher levels of extracellular noradrenaline levels (Fig. 2d). 25/01/2018 Pim - Because the paper shows uptake after stimulation (=release) the term 'neurotransmitter reuptake (GO:0098810)' rather than uptake could be selected.. Experimental description: Characterization of NET-/- mice