• Facets (new session)
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  • Rule: ActivityStreamsMapasEquivalentb3sb3sifpccisofacetshttp://demo.openlinksw.com/dataspacehttp://www.w3.org/2002/07/owl#ldpoplwebrel-me-authskos-transsql-vdb-data-lakeurn:ALKAdatareducedurn:analytics:acqof:ruleurn:clothing:rule:qaurn:det:rdf:labelurn:inference:oplfaq:ruleurn:inference:product:feature:inverse:ruleurn:ingleng:inf:demo:inf:ruleurn:kbpedia:actor:subclass:test:rulesurn:kbpedia:comedian:owl:equivalent:class:subproperty:inference:rulesurn:kbpedia:mime-artist:owl:equivalent:class:subproperty:inference:rulesurn:kbpedia:owl:equivalent:class:subproperty:inference:rulesurn:kbpedia:philosopher:owl:equivalent:class:subproperty:inference:rulesurn:kbpedia:stage-actor:owl:equivalent:class:subproperty:inference:rulesurn:kgdemo:1:ifp:ruleurn:kgdemo:1:ifp:rule2urn:lava:demo:ruleurn:owl:equivalent:class:inference:rulesurn:rdfs:subclass:subproperty:inference:rulesurn:rdfs:type:wikidata:ruleurn:recon:data:ifpurn:recon:data:ifp:ruleurn:recruitment:rule:built-in:ruleurn:rsm12e:translation:ruleurn:rxnorm:data:ruleurn:se:demo:inference:ruleurn:test:skos:inverse:ruleurn:wireless:plans:features:builtin:inference:rule:1virtrdf-eturtle-containersvirtrdf-hashtagvirtrdf-ifpvirtrdf-labelvirtrdf-meta-entity-classvirtrdf-urlNone
    
  • Inverse Functional Properties: Disabled (fastest) Apply to subjects only Apply to objects only Apply to both subjects and objects
  • "Same As": Disabled (fastest) Apply to subjects only Apply to objects only Apply to both subjects and objects (recommended) Apply to subjects, objects and predicates (not recommended on big datasets) Apply to predicates only (special use cases only)

Rationale: In subcellular fractionation experiments of rat brain, MacMARCKS was enriched in soluble fractions (S3 and LS2), but also present in most membrane fractions, and in comparison to MARCKS also in the SV fraction (CPG-3) (Fig.5). In isolated synaptosomes, phosphorylation of MacMARCKS by PKC in response to stimulation by phorbol esters or depolarization-induced Ca2+-influx, induces a translocation of MacMARCKS from the membrane to the cytosol (Fig.4). In NGF-differentiated PC12 cells, MacMARCKS colocalizes with the presynaptic marker Synaptophysin (Fig. 3). MacMARCKS is myristoylated and interacts with the plasma membrane. Therefore the term "anchored component of the presynaptic PM" was chosen. Antibody: Affinity purified polyclonal antiserum against murine MacMARCKs. No KO-control.. Experimental description: Figure legend Fig. 4: PKC agonists or depolarization induce the phosphorylation of MacMARCKS in rat brain synaptosomes... Figure legend Fig. 5: Proteins from rat brain subcellular fractions were fractionated...